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Adapt

Antibody-specific epitope prediction




 

Antibody Sequence Load Sample Input

Antigen Sequence Load Sample Input

Antibody PDB
Antigen PDB

Reference PDB (Optional)


Input Requirements (Sequence)

  • Sequences must be amino-acid sequences with no gaps(-) and no ambiguous residues(B, O, U, X, Z).
  • FASTA headers are required to differentiate between different protein chains, but are otherwise ignored.
  • Antibody sequences must contain 2 chains(Heavy/Light) with heavy always coming before light.
  • Antigen sequences must contain less than 7 chains and fewer than 9999 residues total.

Input Requirements (Structure)

  • Structures must be in PDB flat file format. mmCIF or compressed PDB files are not accepted at this time.
  • Antibody structures must contain only 2 chains labeled H and L for Heavy and Light, respectively.
  • Antigen structures must contain less than 7 chains and fewer than 9999 residues total.

Input Requirements (Reference PDB)

  • Structures must be in PDB flat file format. mmCIF or compressed PDB files are not accepted at this time.
  • Antibody chains must be labeled H and L for Heavy and Light, respectively.
  • All other chains in the file will be interpreted to be the antigen.


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