Diego Diez

Diego Diez Associate Professor diez [at] ifrec.osaka-u.ac.jp

Education

BA Biochemistry, Complutense University, Madrid, 2001

PhD Biochemistry, Autonomous University, Madrid, 2006

Publications

Year Authors Title Publication Cites
2013 AP Hutchins, D Diez, D Miranda-Saavedra The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges BRIEFINGS IN FUNCTIONAL GENOMICS, 2013, 12, 489-498 144
2009 CE Wheelock, ÅM Wheelock, S Kawashima, D Diez, M Kanehisa, ... Systems biology approaches and pathway tools for investigating cardiovascular disease MOL. BIOSYST., 2009, 5, 588-602 99
2010 B Morte, A Ceballos, D Diez, C Grijota-Martínez, AM Dumitrescu, ... Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8-and deiodinase-2 … ENDOCRINOLOGY, 2010, 151, 2381-2381 98
2010 D Diez, ÅM Wheelock, S Goto, JZ Haeggström, G Paulsson-Berne, ... The use of network analyses for elucidating mechanisms in cardiovascular disease MOL. BIOSYST., 2010, 6, 289-304 87
2016 W Nakai, T Yoshida, D Diez, Y Miyatake, T Nishibu, N Imawaka, K Naruse, ... A novel affinity-based method for the isolation of highly purified extracellular vesicles SCIENTIFIC REPORTS, 2016, 6, 33935-33935 86
2008 D Diez, C Grijota-Martinez, P Agretti, G De Marco, M Tonacchera, ... Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum ENDOCRINOLOGY, 2008, 149, 3989-3989 71
2015 I Bahrini, J Song, D Diez, R Hanayama Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia SCIENTIFIC REPORTS, 2015, 5, 7989-7989 63
2013 AP Hutchins, D Diez, Y Takahashi, S Ahmad, R Jauch, ML Tremblay, ... Distinct transcriptional regulatory modules underlie STAT3’s cell type-independent and cell type-specific functions NUCLEIC ACIDS RESEARCH, 2013, 41, 2155-70 59
2011 C Grijota-Martínez, D Díez, G Morreale de Escobar, J Bernal, B Morte Lack of action of exogenously administered T3 on the fetal rat brain despite expression of the monocarboxylate transporter 8 ENDOCRINOLOGY, 2011, 152, 1713-1721 59
2010 B Morte, D Díez, E Ausó, MM Belinchón, P Gil-Ibáñez, C Grijota-Martínez, ... Thyroid hormone regulation of gene expression in the developing rat fetal cerebral cortex: prominent role of the Ca2+/calmodulin-dependent protein kinase IV pathway ENDOCRINOLOGY, 2010, 151, 810-810 58
2014 D Diez, A Agustí, CE Wheelock Network analysis in the investigation of chronic respiratory diseases. From basics to application AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 190, 981-988 41
2013 AP Hutchins, S Liu, D Diez, D Miranda-Saavedra The repertoires of ubiquitinating and deubiquitinating enzymes in eukaryotic genomes MOLECULAR BIOLOGY AND EVOLUTION, 2013, 30, 1172-1187 40
2011 D Díez, F Sanchez-Jimenez, JAG Ranea Evolutionary expansion of the Ras switch regulatory module in eukaryotes NUCLEIC ACIDS RESEARCH, 2011, 39, 5526-5537 25
2013 R Stojnic, D Diez PWMEnrich: PWM enrichment analysis R PACKAGE VERSION 4 (0), 10., 2013, 18129 24
2007 D Diez, R Alvarez, A Dopazo Codelink: an R package for analysis of GE healthcare gene expression bioarrays BIOINFORMATICS, 2007, 23, 1168-1168 24
2013 D Diez, AP Hutchins, D Miranda-Saavedra Systematic identification of transcriptional regulatory modules from protein–protein interaction networks NUCLEIC ACIDS RESEARCH 42 (1), E6-, 2013, 6 22
2012 D Diez, S Goto, JV Fahy, DJ Erle, PG Woodruff, ÅM Wheelock, ... Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics BMC MEDICAL GENOMICS, 2012, 5, 27-27 21
2008 CN Hayes, D Diez, N Joannin, W Honda, M Kanehisa, M Wahlgren, ... varDB: a pathogen-specific sequence database of protein families involved in antigenic variation BIOINFORMATICS, 2008, 24, 2564-2565 20
2013 AP Hutchins, D Diez, D Miranda-Saavedra Genomic and computational approaches to dissect the mechanisms of STAT3’s universal and cell type-specific functions JAK-STAT, 2013, 2, 25097 19
2009 L Folkersen, D Diez, CE Wheelock, JZ Haeggström, S Goto, P Eriksson, ... GeneRegionScan: a Bioconductor package for probe-level analysis of specific, small regions of the genome BIOINFORMATICS, 2009, 25, 1978-1979 12
2010 D Diez, N Hayes, N Joannin, J Normark, M Kanehisa, M Wahlgren, ... varDB: A database of antigenic variant sequences—Current status and future prospects ACTA TROPICA, 2010, 114, 144-151 5
2016 A Bueno, I Morilla, D Diez, AA Moya-Garcia, J Lozano, JAG Ranea Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies ONCOTARGET, 2016, 7, 75810-75810 3
2017 B Nosirov, J Billaud, A Vandenbon, D Diez, E Wijaya, KJ Ishii, ... Mapping circulating serum miRNAs to their immune-related target mRNAs ADVANCES AND APPLICATIONS IN BIOINFORMATICS AND CHEMISTRY: AABC, 2017, 10, 1-1 1
2011 GM Kirwan, D Diez, JZ Haeggström, S Goto, CE Wheelock Systems Biology Approaches for Investigating the Relationship Between Lipids and Cardiovascular Disease CURRENT CARDIOVASCULAR RISK REPORTS, 2011, 1-10 1
2009 CN Hayes, D Diez, N Joannin, M Kanehisa, M Wahlgren, CE WHEELOCK, ... Tools for investigating mechanisms of antigenic variation: new extensions to varDB GENOME INFORMATICS 2009: GENOME INFORMATICS SERIES VOL., 2009, 23, 46-59 1
2019 A Vandenbon, D Diez singleCellHaystack: Finding surprising genes in 2-dimensional representations of single cell transcriptome data BIORXIV, 2019, 557967 0
2015 D Diez rTRMui: a shiny user interface for the identification of transcriptional regulatory modules , 2015 0
2014 D Diez rTRM: an R package for the identification of transcription regulatory modules (TRMs) , 2014 0
2013 D Diez Codelink Legacy: the old Codelink class , 2013 0
2012 D Miranda-Saavedra, A Hutchins, S Poulain, D Diez Control of the anti-inflammatory response by STAT3 IMMUNOLOGY, 2012, 137 0
2011 FL D'Alexandria, D Grapov, P Golapacharyulu, D Diez, S Goto, ... Systems-based approaches to elucidating gender-specific mechanisms in the etiology of atherosclerosis METABOMEETING, 2011, 2011, 27-27 0
2011 J Bernal, D Díez, C GRIJOTA-MARTINEZ, G Morreale de Escobar, ... Lack of Action of Exogenously Administered T3 on the Fetal Rat Brain Despite Expression of the Monocarboxylate Transporter 8 , 2011 0
2010 E Ausó, M Belinchón, P Berbel, J Bernal, D Díez, P Gil-Ibáñez, ... Thyroid hormone regulation of gene expression in the developing rat fetal cerebral cortex: prominent role of the Ca2+/calmodulin-dependent protein kinase IV pathway , 2010 0
2010 J Bernal, A Ceballos, C Di Cosmo, D Díez, AM Dumitrescu, VA Galton, ... Thyroid Hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hotmone: a study in monocarboxylate transporter-8-and deiodinase-2 … , 2010 0
2009 D Diez, M Kanehisa, S Goto Evolution of antigenic gene families in the Plasmodium genus , 2009 0
2009 D Diego, K Minoru, G Susumu Evolution of antigenic gene families in the Plasmodium genus (数理モデル化と問題解決 (MPS) Vol. 2009-MPS-76) 研究報告数理モデル化と問題解決 (MPS), 2009, 2009, 1-12 0
2008 P Agretti, J Bernal, G De Marco, D Díez, C GRIJOTA-MARTINEZ, ... Thyroid Hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat stratum , 2008 0
2008 CN Hayes, D Diez, N Joannin, M Kanehisa, S Goto Improving alignment of hypervariable regions for varDB GIW, 2008, 2008 0
2008 D Diez, N Hayes, N Joannin, M Kanehisa, M Wahlgren, CE Wheelock, ... A framework for mining GenBank: Implementation for the varDB project GIW, 2008, 2008 0
2006 D Diez, U Ribacke, C Wheelock, M Wahlgren, S Goto Analysis of the Sub-Telomeric Region of the Malaria Parasite P. falciparum Using aCGH Data GIW, 2006, 2006 0
PAGETOP